|
KMID : 0363220100480050424
|
|
Korean Journal of Dermatology
2010 Volume.48 No. 5 p.424 ~ p.428
|
|
|
A Case of Squamous Cell Carcinoma of the Liver in a Patient with Arsenic Keratosis Associated with Multiple Bowen`s Disease
|
|
Lee Eun-Ah
Park Young-Min
Kim Hyung-Ok
Kim Hei-Sung
|
|
|
Abstract
|
|
|
|
Arsenic keratosis can be a precursor of both Bowen’s disease and squamous cell carcinoma. In fact, there is a direct dose-response relationship between the amount of arsenic exposure and the development of skin cancer. Therefore, meticulous dermatologic surveillance and follow-up are advised to detect malignancy at an early and curable stage. We herein report on a case of a 62-year-old man who presented with multiple Bowen’s disease and arsenic keratosis. His past history revealed chronic exposure to arsenic through consumption of Chinese traditional herbal medicine. After a follow-up loss of 2 years, he returned with multiple extracutaneous metastases of squamous cell carcinoma, including the liver. Our case emphasizes the importance of regular follow-up and survey for skin cancer and other internal malignancies in patients with history of chronic arsenic exposure.
|
|
|
KEYWORD
|
|
|
Arsenic keratosis, Bowen’s disease, Squamous cell carcinoma of liver
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
  
|